Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice
نویسندگان
چکیده
منابع مشابه
Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum.
Evidence from clinical trials of malaria vaccine candidates suggests that both cell-mediated and humoral immunity to pre-erythrocytic parasite stages can provide protection against infection. Novel pre-erythrocytic antibody (Ab) targets could be key to improving vaccine formulations, which are currently based on targeting antigens such as the circumsporozoite protein (CSP). However, methods to ...
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R.K. Tyagi1,2*, N.K. Garg3, T. Sahu4 and P. Prabha5 1Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, 2Malaria Vaccine Development Laboratory, Institute Pasteur Paris, 3Shantha Biotechnics Ltd., (A Part of Sanofi Aventis Group), Hyderabad, AP, 4National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, ...
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ژورنال
عنوان ژورنال: npj Vaccines
سال: 2017
ISSN: 2059-0105
DOI: 10.1038/s41541-017-0028-2